Understanding Prostate Cancer Coursera Quiz Answers

Get All Weeks Understanding Prostate Cancer Coursera Quiz Answers

Welcome to Understanding Prostate Cancer. My name is Ken Pienta, Professor of Urology and Oncology at the Johns Hopkins School of Medicine. I have been studying prostate cancer and treating patients with prostate cancer for over 25 years.

Over 1,000,000 men worldwide and 230,000 men in the United States are diagnosed with prostate cancer every year. Three hundred thousand men worldwide and 30,000 men in the US are dying from prostate cancer every year.

As people live longer, the incidence of prostate cancer is rising worldwide and prostate cancer continues to be a major health problem. Thanks to years of dedication and commitment to research we’ve made enormous advances in the treatment of prostate cancer, But there is still a lot of work to be done.

In this Understanding Prostate Cancer course, I will provide an introduction to the biology of prostate cancer as well as how it is identified and treated at various stages of the disease.

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Understanding Prostate Cancer Coursera Quiz Answers

Biology, Incidence, and Risk Factors for Prostate Cancer Quiz Answers

Q1. What are the risk factors for prostate cancer?

  • + Family history, African American Race, Age
  • Smoking
  • + Family history, Asian Race, Age
  • Alcohol abuse

Q2. Who should discuss prostate cancer screening with their health care provider?

  • A 38 year old man
  • A 80 year old man with a life expectancy of 5 years
  • A 60 year old African American man
  • All of these options

Q3. PSA is the abbreviation for:

  • Prostate Sensitive Antigen
  • Prostate Specific Antigen
  • Prostate cancer
  • Benign Prostate Hyperplasia

Q4. Benign Prostatic Hyperplasia

  • Is an infection of the prostate
  • Is a benign enlargement of the prostate that occurs with age in some men
  • Is a form of lethal prostate cancer
  • Puts a man at higher risk of developing prostate cancer

Q5. The Prostate

  • Is found in the neck
  • Is a gland about the size of the walnut that sits below the bladder
  • Is found in the brain
  • Is found in women

Q6. Prostate Cancer

  • Is the most common non-skin cancer discovered in men
  • Is a form of sarcoma
  • Is the most common cancer found in women
  • Is usually found in children

Q7. What is cancer?

  • Is a benign enlargement of a gland that occurs with age
  • It is a disease that never kills a person
  • It means uncontrolled growth
  • Is an infection that is treated with antibiotics

Q8. Cancer is a disease of multiple genetic alterations

  • False
  • True

Q9. Most of the time, a single mutation is not sufficient to cause cancer

  • True
  • False

Q10. Prostate Cancer is considered to be what type of cancer?

  • A lymphoma
  • A leukemia
  • A pediatric sarcoma
  • An adenocarcinaoma

Q11. A normal PSA is over 100 ng/mL:

  • False
  • True

How Prostate Cancer is Found, Diagnosed, and Staged Quiz Answers

Q1. A bone scan:

  • Detects prostate cancer that has spread to the brain
  • Finds prostate cancer cells circulating in the blood
  • Can help detect if bone is being damaged by prostate cancer
  • Identifies cancer that has spread to lymph nodes

Q2. A CT Scan:

  • Can help identify cancer that has spread to lymph nodes
  • Uses sound waves to create an image of the body
  • Is a blood chemistry test
  • Is never used to find prostate cancer that has spread outside of the prostate

Q3. Gleason Grade 3:

  • Consists of small glands that are fusing together
  • Consists of sheets of cancer cells without gland architecture
  • Is also termed PIN
  • Consists of small, non-fused glands

Q4. M1 disease:

  • Means that cancer has spread to the lymph nodes
  • Refers to tumor size
  • Is not used in prostate cancer staging
  • Means that cancer has not spread beyond the prostate

Q5. Stage T2:

  • Refers to prostate cancer that has invaded the rectum
  • Refers to prostate cancer that is confined to the gland
  • Refers to prostate cancer that has invaded the seminal vesicles
  • Refers to prostate cancer that has invaded the bladder

Q6. N1 disease:

  • Refers to prostate cancer that has spread to the lymph nodes
  • Refers to tumor size
  • Refers to prostate cancer that has spread to the bones
  • Refers to prostate cancer that is organ confined

Q7. Stage T3b:

  • Refers to prostate cancer that has spread to the bones
  • Refers to prostate cancer that has spread outside and is invading the seminal vesicles
  • Refers to prostate cancer that has spread to the lymph nodes
  • Refers to prostate cancer that is organ confined

Q8. An Ultrasound test:

  • Uses radiation to determine the location of prostate cancer
  • Can help determine the size of the prostate
  • Is used to find prostate cancer that has spread to the bones
  • Is never used to help diagnose prostate cancer

Q9. A normal prostate:

  • Is found in women
  • Has large glands and each gland has two cell layers
  • Has no glands
  • Has small glands and each gland has one cell layer

Q10. A MRI

  • Can help determine if prostate cancer has broken through the capsule of the prostate
  • Is used to find prostate cancer that has spread to the bones
  • Is never used to help diagnose prostate cancer
  • Uses radiation to determine the location of prostate cancer

How Localized Prostate Cancer is Treated Quiz Answers

Q1. Potential side effects of radical prostatectomy surgery include (choose the best answer):

  • Incontinence and Erectile dysfunction
  • Erectile dysfunction
  • Hot flashes
  • Incontinence

Q2. Potential side effects of hormonal therapy include (choose the best answer):

  • All of these options
  • Hot flashes
  • Loss of libido
  • Loss of muscle mass

Q3. Intermediate risk prostate cancer includes men with Gleason 8-10 disease.

  • False
  • True

Q4. A man with primary Gleason pattern 5 is defined as having intermediate risk prostate cancer.

  • False
  • True

Q5. Active surveillance may be an appropriate therapy for:

  • Prostate cancer that has spread to the lymph nodes
  • Very high risk prostate cancer
  • Very low risk prostate cancer
  • High risk prostate cancer

Q6. Radical prostatectomy can be curative for prostate cancer in men with:

  • Metastatic prostate cancer to the liver
  • Metastatic prostate cancer to the bone
  • Intermediate grade prostate cancer confined to the prostate
  • Metastatic prostate cancer to the lymph nodes

Q7. External beam radiation therapy can be curative for prostate cancer in men with:

  • Intermediate grade prostate cancer confined to the prostate
  • Metastatic prostate cancer to the bone
  • Metastatic prostate cancer to the liver
  • Metastatic prostate cancer to the lymph nodes

Q8. Low risk prostate cancer includes men with Gleason 7 disease.

  • True
  • FalseQ

Q9. Radical prostatectomy and external beam radiation therapy are generally considered to be equally curative for localized and intermediate risk disease.

  • True
  • False

Q10. External beam radiation therapy + 2-3 years of hormonal therapy is the therapy of choice for locally advanced disease

  • False
  • True

Treatment of Metastatic Prostate Cancer Quiz Answers

Q1. What does castration therapy do?

  • Lowers circulating testosterone
  • Permanently increase circulating testosterone
  • Causes men to grow taller
  • Permanently increases circulating estrogen

Q2. LHRH analog drugs work by:

  • Decreasing testosterone synthesis by nerve cells in the brain
  • Block testosterone binding to the androgen receptor
  • Decreasing growth hormone synthesis by the testis
  • Decreasing testosterone synthesis in the testis

Q3. What does abiraterone therapy do?

  • Blocks synthesis of testosterone
  • Causes men to grow taller
  • Blocks testosterone from binding to the androgen receptor
  • Increases the level of circulating testosterone

Q4. What does enzalutamide therapy do?

  • Decreases growth hormone synthesis by the testis
  • Blocks synthesis of testosterone
  • Decreasing testosterone synthesis by nerve cells in the brain
  • Block testosterone binding to the androgen receptor

Q5. What does docetaxel therapy do?

  • Acts as a systemic radionuclide
  • Increases the level of circulating testosterone
  • Blocks testosterone from binding to the androgen receptor
  • Attacks dividing cancer cells by blocking cell division

Q6. What does radium-223 therapy do?

  • Blocks synthesis of testosterone
  • Acts as a vaccine therapy for prostate cancer
  • Acts as a systemic radionuclide to deliver radiation where bone is being remodeled
  • Attacks dividing cancer cells by blocking cell division

Q7. The two supra-castration agents currently approved for castrate resistant prostate cancer are:

  • Abiraterone and Enzalutamide
  • Docetaxel and Enzalutamide
  • Docetaxel and Sipuleucel – T
  • Radium-223 and Abiraterone

Q8. The first line chemotherapy for metastatic castrate prostate cancer is:

  • Bicalutamide
  • Abiraterone
  • Docetaxel
  • Sipuleucel – T

Q9. A phase III clinical trial:

  • Compares the new drug to the standard of care
  • Is done to find out how toxic the new therapy is
  • Determines if the new therapy has any activity against a cancer
  • Tests a new therapy in monkeys

Q10. A phase I clinical trial:

  • Compares the new drug to the standard of care
  • Finds the maximally tolerated dose of a new agent
  • Determines how efficacious the agent is against a cancer
  • Tests the new agent in mice

Other Treatments to Support the Health of Prostate Cancer Patients Quiz Answers

Q1. Potential side effects of castration therapy include:

  • All of these options
  • Weight gain
  • Loss of libido
  • Hot flashes

Q2. Depression is an often overlooked side-effect of castration therapy:

  • True
  • False

Q3. A DEXA scan:

  • Measures PSA
  • Measures testosterone levels in the blood
  • Measures bone mineral density
  • Is a very painful test involving needles inserted into the body

Q4. Two drugs approved for slowing osteoporosis in men on androgen deprivation therapy are:

  • Vitamin C and Vitamin E
  • Difungomuctane and gasoline
  • Zoledronic acid and denosumab
  • Aspirin and acetaminophen

Q5. Alprostadil:

  • Causes blood vessels in the penis to constrict
  • Can be used to treat erectile dysfunction (ED)
  • Is only available as an injection
  • Is only available as a rectal suppository

Q6. Erectile dysfunction can be treated with:

  • Vacuum constriction device
  • Alprostadil
  • Penile implant
  • All of these options

Q7. The most common place that prostate cancer spreads to at the end of life is:

  • Brain
  • Bones
  • Heart
  • Stomach

Q8. Bone pain can be treated with:

  • acetominophen
  • Opiates
  • NSAIDs
  • All of these options

Q9. Breast tenderness is a common side effect of androgen deprivation therapy:

  • True
  • False

Q10. Loss of muscle mass is a common side effect of androgen deprivation therapy:

  • False
  • True
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